华法林计算公式.xls

IWPC Warfarin Dose Calculator
detailed instructions and examples can be found at the Instructions tab
Variable Units or Allowed Values Enter Value
Age Years
Height Centimeters (cm)
Weight Kilograms (kg)
VKORC1 genotype A/A
A/G
G/G
U ((for Unknown)
CYP2C9 genotype *1/*1
*1/*2
*1/*3
*2/*2
*2/*3
*3/*3
U (for Unknown)
Race A (for Asian)
B (for Black or African American)
C (for Caucasian or White)
U (for Unknown or Mixed Race)
Taking Enzyme Inducer Y (for Yes)
N (for No or not known)
Taking Amiodarone Y (for Yes)
N (for No or not known)

Computed Weekly Starting Dose (mg/week): ERROR


























Error Messages/Warnings Validation Result
Enter a numerical value for age in years, such as 65 Error
Enter a numerical value for Height in cm Error BMI calc assuming metric Obesity Descriptor
Enter a numerical value for Weight in kg Error #DIV/0! #DIV/0!
Enter a genotype for VKORC1 -1639 A>G SNP, using one of the allowed values shown in column B, or enter the single letter 'U' for unknown genotype Error
Enter a genotype for CYP2C9, using one of the allowed values shown in column B, or enter the single letter 'U' for unknown genotype, Note that alleles other than *1, *2, and *3 are not allowed in the IWPC algorithm Error
Enter patient's race, using singe letter values A, B, C, or U, as shown in column B Error
Enter either Y (patient taking CYP2C9 inducer) or N (patient not taking CYP2C9 inducer). The inducers considered in development of the IWPC algorithm were rifampin, phenytoin, and carbamazepine Error
Enter either Y (patient taking amiodarone) or N (patient not taking amiodorone). Error

There are 8 errors in the data you have entered. A dose cannot be calculated until the errors are fixed. 8 Error count
0 Warning count

CYP2C9 lookup table
*1/*1 0
*1/*2 -
*1/*3 -
*2/*2 -
*2/*3 -
*3/*3 -
U -