Stargardt病的临床表现及眼底荧光素与吲哚青绿血管造影.doc

Stargardt病的临床表现及眼底荧光素与 吲哚青绿血管造影         【摘要】目的研究Stargardt病的临床表现及吲哚青绿血管造影(indocyaninegreenangiography,ICGA)在该病研究中的价值。方法对25例Stargardt病患者进行眼底荧光血管造影(fundusfluoresceinangiography,FFA)和ICGA检查。结果 %,眼底均有萎缩性黄斑病变,多为青灰色横椭圆形,~。%的眼底有黄色斑点。FFA检查全部黄斑部病变均为强透见荧光,典型者呈“牛眼”状,%的眼底呈现暗脉络膜背景荧光。ICGA早期,黄斑部可见弱荧光区,以后显露不同层次的脉络膜血管形态;眼底黄色斑点为弱荧光。结论 ICGA与FFA结合使用对Stargardt病的临床特征与病理机制研究有帮助。【关键词】 Stargardt病荧光素血管造影术吲哚花青绿/诊断应用血管造影术黄斑变性中国书资料分类法分类号 ′sdiseaseZhangChengfen,ChenYouxin,XuHaifeng,,PekingUnionMedicalCollegeHospital,ChineseAcademyofMedicalSciences,PekingUnionMedicalCollege,Beijing100730,China【Abstract】 Purpose ToinvestigatetheclinicalcharacteristicsoftheStargardt′sdiseaseandtoevaluatethevalueofthefundusfluoresceinangiography(binedwithindocyaninegreenangiography(ICGA)inStargardt′sdisease. Methods Routineeyeexamination, VEP,ERG,EOG,andperimetrywereperformedin25cases(30eyes)ofStargardt′sdisease(15menand10 women) aged12~41, (30eyes),andICGAwasdonein10cases(20eyes). Results %,~%,window