297例女阴尖锐湿疣与假性湿疣临床病理观察 摘要目的:探讨女阴尖锐湿疣及假性湿疣的临床病理诊断和鉴别诊断依据。方法:收集297例患者的临床资料,观察尖锐湿疣及假性湿疣临床和病理学特点,部分病例做免疫组化人乳头瘤病毒检测。结果:真假湿疣发病年龄高峰差异不大。部位:尖锐湿疣多为两个以上部位同时发生,而假性湿疣多数只限于一个部位。局部表现,两种病变均形成乳头状突起,是临床误诊原因之一,但尖锐湿疣常融合成菜花状。组织学观察,鳞状上皮乳头状增生及诊断性空泡细胞是尖锐湿疣的主要诊断依据,假性湿疣中非诊断性空泡化细胞是病理诊断误诊原因之一。免疫组化染色,尖锐湿疣细胞核阳性率为63%,假性湿疣为阴性。结论:诊断性空泡细胞及人乳头瘤病毒检测阳性是目前诊断尖锐湿疣和鉴别假性湿疣的重要依据。关键词尖锐湿疣;诊断,鉴别中分类号 文献标识码 A文章编号 1001-7399(2000)04-0283-03Aclinicopathologicalobservationof297casesofcondylomaandpesudo-condylemainfemalevulvaSunFengping(DeptofPathol,SecondHospitalofShaoxingCity,ZhejiangProvince 212000)BaoLei,CaiHongguang,YangHuiying(DeptofPathol,ShaoxingWomenandChildrenHospital 312000)ABSTRACT Purpose Toprobetheevidenceforthepathologicaldiagnosisanditsdifferentialdiagnosisofcondylomaandpseudo- Atotalof297casesofcondylomaandpseudo-condylomawerestuditedclinicallyandpathologically, Onsetage:nosignificantdifferencewasobservedonthepeakonset-:uresimultaneouslyatmorethantwosites,whilethepseudu-condylomata,mostofthem,:thepapillapyprocess,whichoftenledtotheclinicalmisdiagnoses,,:
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