抗甲状腺药物治疗孕妇甲状腺功能亢进的疗效以及对胎儿的影响 【摘要】目的:探讨抗甲状腺药物治疗孕妇甲状腺功能亢进的疗效以及对胎儿的影响。方法:将70例甲状腺功能亢进的孕妇按照是否接受抗甲状腺药物治疗分为两组,研究组和对照组,研究组孕妇给予抗甲状腺药物治疗,而对照组孕妇拒绝接受抗甲状腺药物治疗。观察并比较两组患者的疗效以及胎儿的发育情况。结果:研究组孕妇足月顺产30例,早产5例;对照组孕妇流产或死胎15例,足月顺产15例,早产5例。两组新生儿在性别、胎龄、出生体重等反面比较差异均无统计学意义(均P>)。%(27/35);%(10/35)(P<)。研究组和对照组新生儿FT3、FT4、TT4水平没有显著差异(均P>)。结论:抗甲状腺药物治疗孕妇甲状腺功能亢进可显著促进孕妇的健康,且对胎儿无明显副作用。 【关键词】抗甲状腺药物;孕妇;甲状腺功能亢进;疗效;胎儿 Effect of anti thyroid drug in treatment of pregnant women with hyperthyroidism and its effects on the fetus [Abstract] Objective: To study the effect of anti thyroid drug in treatment of pregnant women with hyperthyroidism and the effects on the fetus. Methods: 70 cases of pregnant women with hyperthyroidism were divided into two groups, the study group and the control group, according to whether or not to accept the antithyroid drug for treatment, the pregnant women in the study group were given anti thyroid drug for treatment while the pregnant women in the control group refused to accept the antithyroid drug for treatment. The efficacy and the development of the fetus were observed pared between the two groups of patients. Results: The study group had 30 cases of full-term pregnant women, 5 cases of premature labor; the control group had 15 cases of miscarriage or stillbirth, 15 cases of full-term normal delivery, 5 cases of preterm labor. Two groups of neo