芪苈强心胶囊对慢性充血性心力衰竭患者心功能及同型半胱氨酸的影响.doc

芪苈强心胶囊对慢性充血性心力衰竭患者心功能及同型半胱氨酸的影响.doc芪苈强心胶囊对慢性充血性心力衰竭患者心功能及同型半胱氨酸的影响[ 摘要] 目的观察芪苈强心胶囊对慢性充血性心力衰竭( CHF ) 患者心功能及同型半胱氨( Hcy ) 的影响。方法 2013 年4 月~ 2014 年 12月, 将 140 例 CHF 患者随机分为观察组和对照组。两组均给予抗心力衰竭等常规西医治疗,观察组在常规西医治疗基础上加用芪苈强心胶囊,疗程为 8 周。观察治疗前后患者的临床症状,6 min 步行试验距离( 6MWD ), 检测血清同型半胱氨酸( Hcy ) 和测定左室射血分数( LVEF )。结果观察组的显效率、总有效率均明显高于对照组( P< ) ;治疗后,两组患者的 LVE F 明显提高,血清 Hcy 水平明显下降, 6MWD 明显增加( P< ) ;与对照组比较,观察组治疗后的 LVEF 显著提高,血清 Hcy 水平显著下降, 6MWD 显著增加( P< )。结论常规西医治疗基础上加用芪苈强心胶囊治疗 CHF 可增加 LVEF 、 6MWD 距离,降低血清 Hcy 水平,明显改善心功能,提高临床疗效。[ 关键词] 芪苈强心胶囊;充血性心力衰竭;心功能;同型半胱氨酸[ 中图分类号] +1 [ 文献标识码]A[ 文章编号] 1674-4721 ( 2015 ) 09(a) -0039-03 [Abstract] Objective To observe the influence of Qiliqiangxin capsule on cardiac function and homocysteine ( Hcy ) in patients with chronic congestive heart failure ( CHF ). Methods From April 2013 to December 2014 , One hundred and forty patients CHF with were randomly divided into observation group and control western therapy of anti-heart failure was provided in both the basis of the regular western therapy , Qiliqiangxin capsule in observation group was added , and course of treatment lasted 8 symptoms and 6-minute walking test distance ( 6MWTD ) before and after treatment were Hcy and left ventricular ejection fraction ( LVEF ) were determined. Results The marked improvement rate and total effective rate in observation group was obviously higher t